Germinal matrix hemorrhage-intraventricular hemorrhage: pathogenesis and outcomes

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Germinal matrix hemorrhage-intraventricular hemorrhage: pathogenesis and outcomes

Germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) is one of the CNS injuries affecting preterm infants occurring in about 15%–20% of subjects weighing less than 1500 g. Currently, using ultrasonography, we recognize three grades of GMH-IVH. Grade I involving the subependymal parenchyma and/or extending in less than 10% of the ventricle, grade II with intraventricular bleeding not...

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Preventing Germinal Matrix Layer Rupture and Intraventricular Hemorrhage

The etiology of intraventricular hemorrhage (IVH) in extremely low birth weight preterm infants is multifactorial with circulatory instability and hemostasis being preeminent. This study sought to determine if the germinal matrix layer remained intact when platelets were above 200 × 10(9)/L, a near normal level, and fell below that when IVH occurred. This was a retrospective study of platelets ...

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Risk Factors of Germinal Matrix Intraventricular Hemorrhage in Premature Infants

OBJECTIVE To determine whether some clinical parameters can be used to predict the hemorrhage and whether the relationship between these clinical variables and the grades of hemorrhage is linear. METHODS A total of 230 premature infants, born at a gestational age less than 34 weeks were retrospectively reviewed. Germinal matrix-intraventricular hemorrhage (GM-IVH), the grade of the hemorrhage...

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Impaired Neurodevelopmental Outcome After Mild Germinal Matrix-Intraventricular Hemorrhage.

Germinal matrix–intraventricular hemorrhage (GMH-IVH) is a common and characteristic form of intracranial hemorrhage occurring in the premature infant. The hemorrhage originates in small blood vessels in the subependymal germinal matrix (also termed the ganglionic eminence) and may disrupt the ependymal lining and extend into the lateral ventricle. Severe IVH consists of large amounts of intrav...

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Germinal matrix hemorrhage: intraventricular hemorrhage in very-low-birth-weight infants: the independent role of inherited thrombophilia.

BACKGROUND AND PURPOSE The etiology of germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) is multifactorial and the role of genetic polymorphisms is unclear. The aim of this prospective study was to evaluate prothrombotic genetic mutations as independent risk factors for the development of all grades of GMH-IVH in very-low-birth-weight infants. METHODS The presence of both facto...

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ژورنال

عنوان ژورنال: Italian Journal of Pediatrics

سال: 2015

ISSN: 1824-7288

DOI: 10.1186/1824-7288-41-s1-a31